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Residual gastric cancer

  Residual gastric cancer (cancer of gastric remnant) is also known as gastric cancer after surgery. It can occur in the residual stomach after subtotal gastrectomy, as well as in the whole stomach after simple gastrojejunal anastomosis, simple perforation repair, or vagotomy. It is generally believed that it should be limited to gastric cancer occurring after surgery for non-neoplastic gastric lesions. If surgery is performed due to malignant lesions, it should refer to gastric cancer occurring 20 years or more after surgery. Residual gastric cancer accounts for 0.4% to 5.5% of gastric cancer. The incidence of residual gastric cancer is related to the first surgical method. Patients who undergo Billroth II gastrojejunostomy and simple gastrojejunal anastomosis after subtotal gastrectomy are more prone to develop residual gastric cancer than those who undergo Billroth I. The common site of residual gastric cancer is the anastomosis, but it can also occur diffusely in the entire residual stomach.

 

Contents

1. What are the causes of the onset of residual gastric cancer?
2. What complications can residual gastric cancer easily lead to?
3. What are the typical symptoms of residual gastric cancer?
4. How to prevent residual gastric cancer?
5. What laboratory tests are needed for residual gastric cancer?
6. Diet taboos for patients with residual gastric cancer
7. Conventional methods of Western medicine for the treatment of residual gastric cancer

1. What are the causes of the onset of residual gastric cancer?

  1, After a subtotal gastrectomy or vagotomy, the stomach is in a low acid or acid-free state, and the decrease in gastrin secretion leads to a decrease in protective mucus, causing the gastric mucosa to gradually atrophy. The reflux of bile, pancreatic juice, and intestinal juice after gastric surgery also damages the gastric mucosa, leading to chronic atrophic gastritis, intestinal metaplasia, and atypical hyperplasia, which are important reasons for the occurrence of residual gastric cancer.

  2, After gastric surgery, the decrease in gastric acid is conducive to the growth and reproduction of bacteria in the stomach. The metabolic products of bacterial toxins and bile, which are decomposed by bacteria, may have a promoting effect on carcinogenesis. Bacteria containing nitrate reductase can promote the synthesis of carcinogen nitrosamines. Under the action of these carcinogens and promoting carcinogens, the gastric mucosa may undergo malignant transformation.

  3, Scars after gastric surgery, or even the stimulation of non-absorbable sutures, may also be one of the factors leading to residual gastric cancer.

  In summary, gastric surgery changes the normal anatomy and physiological function of the stomach, making the stomach more exposed to carcinogens and promoting carcinogens. When the body's immune function is low, residual gastric cancer can occur.

2. What complications can residual gastric cancer easily lead to?

  Mainly manifested as abdominal pain, vomiting, melena, weight loss, anemia and other complications. After a meal, the sudden expansion of the intestinal lumen increases serotonin release and promotes peristalsis, causing a stimulation response of the celiac plexus. Common clinical symptoms include upper abdominal pain, palpitations, sweating, dizziness, weakness, vomiting, and sometimes pale complexion and diarrhea. Prevention methods: lying flat for 10 to 20 minutes after eating can control or alleviate the symptoms; regulate diet, eat more protein and fat foods.

3. What are the typical symptoms of residual gastric cancer?

  1. After 5 years of gastric resection, persistent upper abdominal pain, decreased appetite, weight loss, persistent occult blood in stool, antacid and antispasmodic agents cannot relieve the pain.

  2, There may be tenderness or palpable masses in the upper abdomen.

4. How to prevent residual gastric cancer

  1, After a subtotal gastrectomy or vagotomy, the stomach is in a low acid or acid-free state, and the decrease in gastrin secretion leads to a decrease in protective mucus, causing the gastric mucosa to gradually atrophy. The reflux of bile, pancreatic juice, and intestinal juice after gastric surgery also damages the gastric mucosa, leading to chronic atrophic gastritis, intestinal metaplasia, and atypical hyperplasia, which are important reasons for the occurrence of residual gastric cancer.

  2, After gastric surgery, the decrease in gastric acid is conducive to the growth and reproduction of bacteria in the stomach. The metabolic products of bacterial toxins and bile, which are decomposed by bacteria, may have a promoting effect on carcinogenesis. Bacteria containing nitrate reductase can promote the synthesis of carcinogen nitrosamines. Under the action of these carcinogens and promoting carcinogens, the gastric mucosa may undergo malignant transformation.

  3, Scars after gastric surgery, or even the stimulation of non-absorbable sutures, may also be one of the factors leading to residual gastric cancer.

  In summary, gastric surgery changes the normal anatomy and physiological function of the stomach, making the stomach more exposed to carcinogens and promoting carcinogens. When the body's immune function is low, residual gastric cancer can occur.

  

5. What laboratory tests are needed for residual gastric cancer

  1, A history of gastric resection for more than 5 years.

  2, Persistent pain in the upper abdomen, decreased appetite, and weight loss.

  3, Persistent positive occult blood in feces.

  4, Barium meal X-ray examination: Most cases show filling defects in the residual stomach, but it should be distinguished from the hyperplasia of benign mucosal folds around the anastomosis. X-ray examination is difficult for early lesions.

  5, Endoscopy is more reliable, and biopsy can be performed for confirmation at the same time.

6. Dietary taboos for patients with residual gastric cancer

  One, Diet

  1, Sugar cane and ginger drink: An appropriate amount of sugar cane and ginger. Squeeze half a cup of sugar cane juice, mix with 1 spoon of ginger juice, and simmer to make a drink. Take twice a week, after simmering, it has the effect of harmonizing the middle energizer and strengthening the stomach, and is suitable for the early stage of gastric cancer.

  2, Brown sugar stewed tofu: 100g of tofu, 60g of brown sugar, and 1 bowl of water. Dissolve the brown sugar in water, add tofu, and boil for 10 minutes. Take regularly, it has the effect of harmonizing the stomach and stopping bleeding, and can be used to treat hematemesis.

  3, Tangerine peel and red date drink: 1 piece of tangerine peel, 3 red dates. Remove the seeds from the red dates and boil them with the tangerine peel to make a decoction. Take once a day, this therapeutic food can promote qi, tonify the spleen, relieve nausea and vomiting, and is suitable for虚寒vomiting.

  4, Radish congee: 30g of radish seeds, and an appropriate amount of glutinous rice. First, roast the radish seeds until they are done, then cook them with glutinous rice to make congee. Take once a day, for breakfast, this prescription can eliminate food accumulation and relieve abdominal distension, and can be used for those with obvious abdominal distension.

  5, Tangerine peel pork congee: 9g of tangerine peel, 12g of cuttlefish bone, 50g of lean pork, and an appropriate amount of glutinous rice. Boil the tangerine peel, cuttlefish bone, and rice together, remove the tangerine peel and cuttlefish bone after boiling, add slices of lean pork and boil again, season with a little salt. Take twice a day, in the morning and evening, this medicinal congee can relieve nausea and vomiting, tonify the spleen and regulate the qi, and can be the first choice for those with abdominal distension.

  6, Lettuce: 250g of lettuce, 250g of dried red dates, 500g of flour. Cut the lettuce into pieces, cook the dried red dates until soft and remove the seeds, then mix with flour to make a cake. It can be taken as a snack, tonifying the spleen and stomach, drying dampness and promoting diuresis; it can be used for loose stools or diarrhea.

  7. Heirloom six-ingredient cake: 30 grams of Euryale ferox, Chinese yam, Poria, lotus seed, Job's tears, and mung bean, 500 grams of rice flour. Process all the above into powder and mix it with rice flour. Take it twice or three times a day, 6 grams each time, add sugar for seasoning, and take it with boiling water, or it can also be made into cakes. This recipe strengthens the spleen and has a good effect on止泻(stopping diarrhea).

  8. Longan and peanut soup: 250 grams of peanuts with the red skin, 5 jujubes, and 12 grams of longan meat. Remove the core of the jujube, and boil it with peanuts and longan together. Take it once a day, it can nourish the blood and strengthen the spleen, and can be used for those with obvious anemia.

  9. Plum vinegar congee: 20 grams of plums, 100 grams of glutinous rice, and an appropriate amount of rock sugar. First, boil the plums to make a concentrated juice and remove the dregs, then cook the glutinous rice into congee, add a little rock sugar to the congee when it is cooked, and then boil it slightly. Take it once a day, this recipe has the effect of astringing and stopping bleeding.

  10. Flaxseed paste: 20 grams of flaxseed, 20 grams of peach kernel, and 80 grams of glutinous rice. Cook the rice congee with flaxseed, peach kernel, and glutinous rice together. Take it every other day, it can moisten intestines and relieve constipation, and can be used for those with dry and constipated stools.

  11. Sesame paste: 6 grams of sesame, 30 grams of glutinous rice, and an appropriate amount of honey. Roast the sesame until fragrant, add it to the rice congee when it is about to be cooked, and then add honey to mix well. Take it once a day, this medicinal diet nourishes the blood and moistens the intestines.

  12. Fish maw crisp: Fish maw (the swim bladders of bighead carp, crucian carp, yellowlip fish, and eel can be used as raw materials), sesame oil. Fry the fish maw with sesame oil until crisp, then crush it. Take 10 grams three times a day, with warm water. This medicinal diet补肾益精, nourishes tendons, stops bleeding, dissipates blood stasis, and reduces swelling.

  13. Healthy stomach and anti-cancer tea: 30 grams of sunflower stalk core or sunflower disk. Boil the above ingredients to make a decoction. Drink the decoction as tea, long-term drinking has the effects of preventing cancer and anti-inflammatory. This diet can be chosen for patients with inflammatory anastomosis after gastric cancer surgery.

  Secondly, postoperative dietary requirements:

  1. Postoperative fasting until gastrointestinal function is restored, removal of the gastric tube, usually 5-7 days.On the day of gastric tube removal, a small amount of water or congee can be taken. On the second day, a small amount of liquid food can be consumed. On the third day, more liquid food can be consumed. On the fourth day, semi-liquid food is recommended, preferably in the form of porridge. From the fifth to the sixth day, soft food can be eaten. From the 7th to the 8th day, normal food can be consumed. There is a medicine that is actually a nutrient, which can be absorbed directly by the human body without gastrointestinal digestion, reducing the burden on the intestines. For example, Ansu, when dissolved in water, can be used as a high-quality liquid diet. Fish soup and meat soup with a little cooked meat residue can be considered as good semi-liquid food. Pay attention to whether there is bloating or abdominal pain during the process of eating. If discomfort occurs, reduce the amount of food and temporarily slow down the transition to normal eating, and continue eating after improvement. For patients with particularly special conditions, dietary issues should be followed according to the doctor's advice.

  2. Pay attention to diet:

  ①Chew slowly: Food stimulates saliva secretion (containing enzymes beneficial for the digestion of carbohydrates) in the mouth, carefully chew, which can make food particles smaller, and mix saliva with food thoroughly, replacing part of the stomach function. 'Chew slowly' refers to two things: 1) swallowing slowly, 2) longer intervals between swallows to prevent the倾倒综合症(syncope) caused by rapid swallowing of a large amount of food (to be elaborated later).

  ② Small and Frequent Meals: After surgery, the capacity of the residual stomach or the connected intestinal segment cannot be compared to before, and the body needs a longer period of time to adapt to this change. Clinical experience shows that it takes at least 8-10 months to recover to normal daily meals of three meals a day. Initially, start with 5-8 meals a day, each meal containing 50-100 grams, and gradually increase the intake according to the patient's tolerance (no bloating or discomfort indicates good tolerance), reducing the frequency of meals. Due to individual differences, the process of adaptation is different.

  ③ Diversified Diet: The variety of food can be chosen according to the patient's dietary preferences and habits, but attention should be paid to consume as many nutritious and easily digestible high-protein, high-vitamin foods as possible. For example, fish, eggs, fresh vegetables, fruits (it is best to drink them as juice), etc. Iron supplementation should be noted because after gastric resection, the stomach acid's role in iron (converting ferric iron to ferrous iron) is lost, causing malabsorption. Some iron preparations can be taken orally under the doctor's guidance, and in daily life, iron pots should be used, and more iron-rich foods such as animal livers, spinach, and soy products should be consumed. Drinking some yogurt is also beneficial.

  ④ Postprandial Position: After surgery to remove the gastric entrance, to prevent food from refluxing after eating, one should maintain a sitting or inclined position; after surgery to remove the gastric outlet, to prevent food from running down too quickly after eating, one should lie down and rest for about 20 minutes before assuming a free position.

  ⑤ After meals, follow the doctor's advice to take some medications, such as digestive drugs, Vitamin B12, Folic acid, etc., which help with digestion and absorption and prevent anemia from occurring.

  3. Foods to be restricted:

  Firstly, foods that are fried, spicy, and刺激性 should be avoided. Raw, cold, and hard foods should also be avoided. Foods that are too hot, too sweet, or too salty should be restricted appropriately.

7. The conventional method of Western medicine for treating residual gastric cancer

  The advantages of traditional Chinese medicine treatment lie in the holistic adjustment and emphasis on reinforcing the body's vital energy. Chinese herbs also excel in enhancing the body's immune function, such as promoting the increase in the number of white blood cells, mononuclear macrophages, strengthening phagocytic function, promoting the transformation of lymphoblasts, and increasing antibody production, which mobilizes the body's anti-cancer factors. In addition, there is also a certain function of promoting hematopoiesis and protecting the bone marrow. Herbs for reinforcing the body's vital energy include Astragalus, Schisandra chinensis, and Ginseng, etc. Therefore, Chinese medicine used after gastric cancer surgery not only promotes the recovery of the patient's body but also improves the quality of life for cancer patients, and can continue to exert anti-cancer effects, which is helpful for reducing mortality and improving survival rates. Since the occurrence and development of gastric cancer is inherently a process of malignant struggle caused by deficiency leading to excess, and excess leading to more deficiency, therefore, when the tumor has not been removed, the treatment should focus on treating the excess, that is, mainly attacking the tumor; if the tumor has been removed, although it does not mean that the root of the problem has been completely removed, the mortal injury to the body has been eliminated, and its process of malignant struggle has also changed accordingly, so there are significant differences in treatment methods compared to those who have not undergone surgery. The latter should focus on reinforcing the body's immune compensatory ability with herbs for reinforcing the body's vital energy. However, the functions of the stomach's descent and the spleen's transportation and transformation should also be strengthened and regulated.

  Therefore, commonly used herbs such as Sheng Huang Qi, Jiao Gu Lan, Hou Gu, Nü Zhen Zi, Dang Shen, Bai Zhu, Fu Ling, Gan Cao, Mu Xiang, Ban Xia, Mai Ya, Ji Ren Jin, etc., not only promote the recovery of postoperative tissue trauma, but also improve the body's immune function, revitalize the body's vital energy, and also promote the production of interferon. Especially in the treatment of cancer in the late stage or during the recovery period, it cannot be ignored. In necessary cases, Mai Dong, Bei Sha Shen, Shi Hu can also be added, especially when patients show signs of Yin fluid deficiency, which is indispensable. Warming and moistening in combination, they can be used concurrently without conflict.

  If surgery is only performed at stage II cancer, it is necessary to prevent the recurrence of residual cancer and the distant metastasis of cancer cells. In this case, antitumor Chinese herbal medicine should also be added according to the symptoms, such as adding She Sheung San, Ban Zhi Lian, Shi Shang Bai, Shi Jian Chuan, etc. if there are signs of heat; adding Guo Lü, Zhe Bei, Mu Li, Kun Bu, Hai Zao, etc. if there are signs of phlegm; adding Dan Shen, Chi Shao, Tao Ren, Zhuang Jie Feng, etc. if there are signs of blood stasis; adding Bai Ji Li, Chuan Miao Zi, Ba Yue Zha, etc. if there are signs of liver depression. Whiteflower, Jin Gang Ci, Long Kui, etc., which have a good inhibitory effect on stomach cancer, can be added according to circumstances to enhance the antitumor effect.

  Some patients may lose the function of the pylorus after surgery, which may cause reflux gastritis or dumping syndrome. The clinical manifestations of the former are vomiting, with yellow or yellow-green vomit, which can be improved with modified Wending decoction; the latter is characterized by a feeling of fullness and nausea in the upper abdomen after eating, belching, followed by diarrhea, accompanied by pale complexion, sweating, palpitations, and dizziness, which can be improved with modified Xiangsha Liujun decoction. In addition, it is also necessary to regulate diet, eat less and more often, and chew slowly.

  In summary, surgery is the preferred treatment for stomach cancer, and it is the only means to clear the tumor and relieve the obstructive symptoms of cancer. Combining traditional Chinese medicine to strengthen the body's resistance is the key to improving the long-term survival rate and quality of life of stomach cancer patients after surgery.

Recommend: Esophageal Rupture Syndrome , Hepatitis C , Fulminant hepatic failure , Smooth muscle sarcoma of the residual stomach , Adult hypertrophic pyloric stenosis , Para-peritoneal hernia

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