Xiaoxintong, a highly effective nitrated ester anti-anginal drug, mainly consists of isosorbide dinitrate. It takes effect within 30 minutes after oral administration, and takes effect within 2 to 3 minutes after dissolution. It is used to alleviate the onset of subacute angina pectoris. Then, what is another name for Xiaoxintong? Below, we will carry out a simple understanding and understanding of this issue, hoping that the following points will be of some help to everyone!

What else is Isordil called?

Isordil is also known as sodium nitroprusside isomers, and its main component is sodium nitroprusside isosorbide. Generally, it takes effect in 30 minutes after oral administration and in 2-3 minutes after sublingual administration. It is mainly used to alleviate acute angina attacks. The effect can last for 2-4 hours, but its efficacy is relatively weak. Generally, patients with low blood pressure and glaucoma cannot use it. It is used for the long-term treatment of coronary heart disease, the prevention of angina, and the treatment of persistent angina after myocardial infarction, as well as the treatment of chronic congestive heart failure.

Isordil characteristics: Tablets.

Isordil efficacy and action: This product is a highly effective nitrate anti-anginal drug, with efficacy similar to nitroglycerin but longer-lasting (can last for more than 4 hours), taking effect in 30 minutes after oral administration, and taking effect in 2-3 minutes after sublingual administration. It is used to alleviate acute angina attacks.

Isordil dosage and administration: Oral: 2-3 times a day, 5-10mg per dose. Sublingual: 2.5-5mg per dose.

Isordil side effects and precautions: 1. There may be a headache reaction, which should start with a low dose and then gradually increase the dose. In addition, there may be facial redness, burning sensation, nausea, vomiting, dizziness, sweating, and even exhaustion. 2. Occasionally, rash, even exfoliative dermatitis may occur. Alcohol can often enhance its side effects.

Isordil specifications: Tablets: 2.5mg, 5mg, 10mg per tablet.

Other: 1. Patients with glaucoma are prohibited from using it. 2. Long-term use can produce tolerance; and there is cross-resistance with other nitrates. 3. Sublingual administration has a good effect, and oral administration is used to prevent attacks. It is often used with propranolol. Others are similar to nitroglycerin.

Is Isordil covered by medical insurance: Medical Insurance. Is Isordil an over-the-counter drug: Prescription.

The common formulations of sodium nitroprusside isomers include oral X-ray films, sustained-release capsules, sublingual tablets, and intravenous Chinese medicine preparations. The oral administration is completely digested and absorbed, with a significant first-pass clearance effect of the liver, dissolution rate of about 20%-25%, X-ray films taking effect in 15-40 minutes, and the efficacy lasting for 2-6 hours; the sustained-release capsules take effect in about 60 minutes, and the efficacy can last for 12 hours. The sublingual administration has a dissolution rate of about 60%, taking effect in 2-5 minutes, reaching a significant effect in 15 minutes, and the efficacy lasting for 1-2 hours. The half-life of the sodium nitroprusside isomers parent drug molecule structure is about 1 hour, with weak specificity, and the key pharmacological efficacy comes from the specific metabolic substances of the liver, 5-mononitrosyl isosorbide, with a half-life of 4-5 hours, while the other metabolic substance, 2-mononitrosyl isosorbide, has basically no clinical manifestations. The metabolic substances are excreted through the kidneys and cannot be eliminated through blood analysis. The half-life of the drug after intravenous injection, sublingual administration, and oral administration is 20 minutes, 1 hour, and 4 hours, respectively.