Sodium Glucose Diphosphate for injection, the scope of application of this product is for the treatment of hypomagnesemia. Hypomagnesemia can occur in subacute conditions, such as during surgical treatment under hemoperfusion, extracorporeal nutrition, and is also related to some chronic diseases, such as chronic alcoholism, long-term malnutrition, and chronic respiratory system decline with depletion of carbonic acid. Let’s take a look at the effects of Sodium Glucose Diphosphate for injection.

Composition 　

Chemical name: Fructose-1,6-bisphosphate fructose trisaccharate octahydrate. 　

Chemical structure: 　

Chemical formula: C6H11O12P2Na3·C8H14O16 　

Molecular weight: 550.17 　

Properties 　

This product is a white or milky white crystalline powder. 　

Indications 　

This product is suitable for low ammonium sulfate urine syndrome. Low ammonium sulfate urine syndrome may occur in acute conditions such as intravenous injection, hemoperfusion during surgical treatment, and parenteral nutrition, and is also related to some chronic diseases such as chronic alcoholism, long-term malnutrition, and chronic respiratory system decline. 　

Specifications 　

(1) 2.5g (2) 5g (3) 7.5g (4) 10g (all calculated without water of crystallization) 　

Dosage and administration 　

Dosage: The recommended dosage is 5-10g per day. The dosage for the treatment of low ammonium sulfate urine syndrome should be based on the level of ammonium sulfate deficiency to prevent ammonium sulfate overload. The maximum recommended dosage is 2 divided doses per day. 　

The dosage for children should be based on body weight (70-160 mg/kg), and should not exceed the recommended dosage. 　

Administration: Dissolve 1g of powder in 10ml of sterile injection water, then intravenously drip the mixed water solution (about 10 mL/min). The mixed water solution must be administered at one time; if not infused, the volume should not be reused. 　

Side effects 　

When the intravenous infusion rate exceeds 10 mL/min, patients may experience facial redness, palpitations, and an itchy sensation in the hands and feet. 　

If side effects are detected, the patient should inform the physician. Reports of allergic reactions and anaphylactic shock are very rare. If allergic reactions occur, stop the drug immediately and provide antiallergic treatment. 　

Treatment for anaphylactic shock: Stop taking the drug, check blood pressure; perform shock-related treatment: intravenous injection of adrenaline, antihistamines, etc. 　

Contraindications 　

Patients with hereditary glucose intolerance, allergic symptoms to this product, hyperammonemia, and renal failure are prohibited from using this product due to allergic symptoms to glucose. 　

Common questions 　

Before administration, it should be observed visually for any special conditions, slight yellowing does not affect the efficacy of the drug. 　

Common questions about medication: Pain and partial irritation may occur when the injection process leaks into the subcutaneous tissue. 　

Caution: Patients with creatinine clearance below 50 mL/min should be tested for blood polyphosphate levels. Children should only be used when necessary and under strict physician guidance. Place children out of reach. 　

Medication during pregnancy and lactation 　

Women in the final three months of pregnancy who receive FDP treatment do not show any significant efficacy. 　

Pediatric medication 　

The physician should think carefully about the clinical situation of children and adolescents. 　

Medication for the elderly 　

No experiments have been conducted on this item, and there are no reliable literature references. 　

Drug interactions 　

This product should not be used concurrently with drugs that do not dissolve between pH 3.5-5.8, nor should it be used with high calcium alkaline solutions. 　

Drug overdose 　

No reports of drug overdose.