We all know that after taking drugs, some side effects may be more prominent, such as vaginal bleeding after taking Megestrol Acetate Tablets, what should we do? What are the details of the instructions for use of Megestrol Acetate Tablets?

Instructions for use of Megestrol Acetate Tablets

Generic name: Megestrol Acetate Tablets

Name:

Trade name:

English name: Megestrol Acetate Tablets

Pinyin letters: Cusuɑn JiɑdiyuntonɡPiɑn

The main component and chemical name of this product:

The main component of this product is: Megestrol acetate. Its chemical name is: 6-hydroxy-17a-methylpregn-4,6-diene-3,20-dione 17-acetate.

Chemical structure: (Refer to Megestrol acetate dispersible tablets of glacial acetic acid)

Chemical formula: C24H32O4

Relative molecular mass: 384.52

Production characteristics of vaccine

This product is in the form of tablets.

Production pharmacology and toxicology of vaccine

This product has a certain inhibitory effect on the release of gonadotropin-releasing hormone from the pituitary gland, but it is weaker than that of levonorgestrel and norethindrone. It does not have the specific estrogen and androgen-like properties, but has a significant anti-estrogenic effect. When used with estrogen, it inhibits ovulation. The fetal malformation experiment in small animals shows that it has the effects of increased fetal mortality rate and fetal malformation in rabbits.

Production pharmacokinetics of vaccine

The half-life of the microorganism drug after oral administration is significantly shorter than that of levonorgestrel, and the vast majority of metabolites are excreted in the form of glucuronate.

Production scope of application of vaccine

Treatment of irregular menstruation, multifunctional uterine hemorrhage, endometriosis; Advanced breast cancer and endometrial adenocarcinoma; It can also be used as the estrogen component of short-acting oral contraceptives.

Production use method and dosage of vaccine

Oral administration: Treatment of amenorrhea due to hypertension (when estrogen levels are sufficient), 4mg once, 2-3 times a day, for 2-3 days continuously, withdrawal bleeding occurs within 2 weeks after drug discontinuation; Hematological treatment of multifunctional uterine hemorrhage, 4-8mg once a day, for a total of 20 days, starting from the 5th day of the menstrual period or concurrent with hypertension; Supplementary treatment for endometriosis, 4-8mg once, 1-2 times a day, starting from the 5th day of the menstrual period, for 3-6 months continuously; Breast cancer with load, 40mg once, 4 times a day, total dose of 160mg per day, for 2 months; Full-term endometrial cancer, 10-80mg once, 4 times a day, total dose of 40-320mg per day, or 160mg once a day.

Production of side effects vaccine

Blood pressure is mainly nausea, dizziness, fatigue; hemorrhagic stroke; supplementation during pregnancy has a relatively definite effect on enhancing the male characteristics of women’s offspring.

Production of contraindications vaccine

Prohibited for severe liver and kidney dysfunction, breast lump, pregnant women.

Production of common questions vaccine

(1) Caution should be exercised in patients with uterine fibroids, venous thrombosis history, hypertension, diabetes, asthma, epilepsy, migraine, and depression.

(2) Pay attention to liver function and breast examination during long-term medication.

Production of medication for pregnant women and during lactation

Prohibited from use.

Production of pediatric medication

Production of medication for elderly patients

Production specifications of vaccine

(1) 1mg (2) 4mg

Production and storage of vaccine

Protect from light, store in a sealed container.

From the instructions for use, we may understand that the drug has this side effect. If the discomfort is severe, it is recommended that patients stop taking the drug and inform the physician to prevent the condition from worsening.

The main component of Methylprednisolone acetate tablets is Methylprednisolone acetate. It can be used for irregular menstruation, multifunctional uterine bleeding, and endometriosis, among others. It can also be used for terminal breast cancer and endometrial cancer.

The dosage for the use of Methylprednisolone acetate tablets is as follows: 1. Functional amenorrhea: oral, 4-8mg per day, for 5-10 days; 2. Endometrial cancer: oral, 100mg per time, three times a day, or oral 500mg, once or twice a day, as a maintenance dose after intramuscular injection.

Methylprednisolone acetate tablets are a semi-synthetic estrogen compound with certain inhibitory effects on hormone-dependent tumors. Its mechanism of action is similar to that of medroxyprogesterone acetate, which may be based on the influence on the metabolism of pituitary gonadotropin, controlling the growth and development of ovarian follicles and growth, thereby reducing the production of estrogen. It acts on estrogen receptors, blocking their production and reuse, affecting their interaction with estrogen, and inhibiting tumor cell growth. In addition, it can also antagonize hormone-dependent protein kinases and affect the interaction between regulatory proteins related to hormone-dependent protein kinases and cell growth and division.

After the above detailed introduction, we firmly believe that everyone has understood that taking Methylprednisolone acetate tablets may have significant side effects. Therefore, patients should be cautious when taking medication, and should not take medication privately to ensure safe and effective medication. It is recommended to use the drug under the specific guidance of a physician to maximize the benefits of the drug and fully exert its therapeutic effects.