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The drug effect time of Betaloc
In simple terms, the longer the drug effect lasts, the better the drug is. The height and depth of the drug effect is affected by many factors, and sometimes even drinking water may affect the drug effect. So, how long can the drug effect of Betaloc last?
The drug effect of Betaloc can generally last for a day. Its continuous maintenance of 24 hours also has a significant assist in the treatment of hypertension, and the antihypertensive effect has a very important clinical significance.
Betaloc was launched in Europe and the United States in 1986, overcoming some shortcomings of the pharmacokinetics of bisoprolol tablets in the past. With only one dose a day, it can achieve a stable half-life of 24 hours and a uniform β1 blockade effect, further improving the efficiency of treatment and quickly being accepted by many clinicians, becoming the more widely used β-blocker in the world at present. It has been used in Europe and the United States for nearly 20 years before officially launching in China.
Generally speaking, compared with Betaloc tablets, bisoprolol tablets, or other sustained-release Chinese medicine preparations, Betaloc sustained-release capsules have more prominent pharmacological advantages, mainly including:
Blood pressure is actually a controlled-release Chinese medicine preparation, after oral administration, the drug is released at a zero-order rate for at least 20 hours, thus the half-life is stable and the peak-valley fluctuations are subtle.
The blood multi-module small bead dosage form has good reproducibility and consistency in drug release, and the pills can be divided for use, enhancing the coordination ability of the dosage.
The supplementation of pharmacokinetic parameters is more stable, mainly manifested as smooth digestion and absorption throughout the digestive tract, unaffected by meals or pH, etc.
In terms of load pharmacodynamics, the overall efficacy of β1 protein kinase blockade within 24 hours is stronger and more stable than that of general tablets. This advantage of Betaloc sustained-release capsules can be converted into taking medication once a day, convenient use, improved patient compliance, reduced side effects, and improved therapeutic effect in clinical care.
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