Levofloxacin eye drops, applicable range includes bacteria susceptible to levofloxacin: Staphylococcus species, Streptococcus species, Streptococcus pneumoniae, Gram-negative bacilli, Enterococcus species, Corynebacterium species, Pseudomonas species, Pseudomonas aeruginosa, Haemophilus species [Haemophilus influenzae, Haemophilus conjunctivae (Koch-Weiss)] Moraxella (Branhamella) catarrhalis, Moraxella streptococci, Moraxella-Abbesii, Serratia species, Klebsiella species, Proteus species, Acinetobacter species, Enterobacter species, Pseudomonas aeruginosa species (propionic acid bacteria). Below, let’s take a comprehensive look at the main uses and instructions for the levofloxacin eye drops. 　

Characteristics 　

This product is a light yellow to pale yellow clear aqueous solution. 　

Indications 　

Sensitivity to bacteria: Staphylococcus species, Streptococcus species, Streptococcus pneumoniae, Gram-negative bacilli, Enterococcus species, Corynebacterium species, Pseudomonas species, Pseudomonas aeruginosa, Haemophilus species [Haemophilus influenzae, Haemophilus conjunctivae (Koch-Weiss)] Moraxella (Branhamella) catarrhalis, Moraxella catarrhalis, Moraxella-Abraham, Serratia species, Klebsiella species, Proteus species, Acinetobacter species, Enterobacter species, Pseudomonas aeruginosa species (propionibacterium). 　

Indications: For the treatment of blepharitis, meibomian glanditis, dacryocystitis, conjunctivitis, meibomian glanditis, keratitis, and for the antiseptic prophylactic therapy during ophthalmic perioperative period. 　

Specifications 　

5ml: 24.4mg (calculated as levofloxacin) 　

Usage and Dosage 　

Generally, 3 times a day, 1 drop per eye, the dosage can be moderately adjusted according to the disease. For the treatment of keratitis, eye drops should be applied every 15 to 30 minutes during the acute phase, and every 5 minutes in the initial 30 minutes for severe cases, and the frequency of eye drops should be gradually reduced after the condition is controlled. Strongly recommended for the treatment of bacterial infection corneal ulcer to use high concentration of antibiotic eye drops. 　

Side effects 　

At the time of application for registration and sale: Among a total of 472 cases, 8 cases (1.69%) had side effects. The key side effects were 4 cases (0.85%) of eye irritation, 3 cases (0.64%) of itching sensation of the upper eyelid, etc. 　

Post-marketing application status survey (7th safety coefficient regular report): Among a total of 6136 cases, 42 cases (0.68%) had side effects. The key side effects were 12 cases (0.20%) of diffuse superficial keratitis and other corneal disorders, 9 cases (0.15%) of blepharitis and other conditions, 6 cases (0.10%) of eye irritation, etc. 　

1. Severe side effects (accidental: less than 0.1%; occasional: 0.1-0.5%; unspecified: more than 5% or frequency unknown): 　

Shock, allergic skin reactions: There is a possibility of causing shock and allergic skin reactions, and sufficient observation should be carried out. When symptoms such as erythema, rash, difficulty breathing, decreased blood pressure, and edema of the eyelids are detected, medication should be discontinued and appropriate treatment should be given. 　

2. Other side effects: Appropriate measures such as discontinuation of medication should be taken when side effects are detected. 　

Contraindications 　

Patients with a history of skin allergies to the ingredients of this product, levofloxacin, and quinolone macrolide antibacterial Chinese medicine preparations. 　

Common questions 　

1. In order to avoid the occurrence of multidrug-resistant bacteria, it should be determined normally to control the duration of taking the medicine as short as possible, within the minimum time required for treating the disease. 　

2. The efficacy of this product against methicillin-resistant Staphylococcus aureus (MRSA) has not been confirmed. When MRSA-induced infections are significant and clinical manifestations do not improve, it is advisable to use drugs with strong anti-MRSA efficacy as soon as possible. 　

3. For eye drops only. 　

4. In order to avoid direct contact of the front end of the container with the periorbital area when eye drops are applied, attention should be paid to prevent environmental pollution droplets.