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Dexamethasone Sodium Phosphate Injection
Adverse effects refer to secondary effects caused in conjunction with the main effects, such as these effects are not necessarily opposite effects, but often not necessary or toxic side effects, patients need to prevent them immediately. Then, what are the adverse effects of Dexamethasone Sodium Phosphate Injection in pregnant women?
Dexamethasone Sodium Phosphate Injection is primarily used for allergic and autoimmune inflammatory diseases, used for connective tissue diseases, active rheumatoid arthritis, rheumatoid arthritis, severe bronchial asthma, severe dermatitis, ulcerative colitis, acute leukemia, and also used for comprehensive treatment of some severe infections and intoxications, as well as malignant lymphoma.
The pharmacokinetics of Dexamethasone Sodium Phosphate Injection is as follows: intramuscular injection of this product reaches the peak blood concentration in 1 hour. The protein binding rate of this product is lower than that of other corticosteroids. The general dose for intravenous injection is 2-20 mg per time; when administered by intravenous infusion, it should be diluted with a 5% glucose injection solution, and can be repeated every 2-6 hours until the condition is stable, but continuous administration of high doses generally does not exceed 72 hours.
The use of Dexamethasone Sodium Phosphate Injection by pregnant women can increase the incidence of placental insufficiency, decreased fetal weight, or intrauterine fetal death, and there is a potential for fetal malformation in animal experiments. Moreover, the administration of high doses to lactating mothers can lead to side effects such as growth inhibition in infants and kidney function impairment, therefore, pregnant women are prohibited from using Dexamethasone Sodium Phosphate Injection.
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Prednisolone Acetate Tablets: Used primarily for various severe subacute bacterial infections, severe allergic diseases, nephrotic syndrome, severe bronchial asthma, thrombocytopenic purpura, leukopenia, subacute lymphangitic sepsis, various adrenal insufficiency syndromes, exfoliative dermatitis, pemphigus, neurodermatitis, eczema, and others.