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What are the main efficacy of ketoconazole capsules?
Ketoconazole capsules are a widely used drug. This drug has no special taste and is a white crystalline powder, often used to treat candidiasis. Candidiasis can cause many diseases in the human body. For example, skin infection can lead to skin diseases, and it can also infect many internal organs, especially the female vagina, so vaginal inflammation often occurs. Candidiasis in the blood of humans can lead to candidemia. In addition to this, the esophagus, urinary system, lower respiratory tract, and other systems of humans may be infected by Candida. At this time, ketoconazole capsules can be used to treat diseases. In addition to these, this drug has many other benefits.
The efficacy and effects of ketoconazole capsules:
Antibacterial drugs generally refer to drugs with bactericidal or bacteriostatic activity. Patients often use this type of drug in daily life, and taking too many antibacterial drugs is also bad for the human body. It should be taken appropriately, and it is better not to use them if possible. Then, what are the efficacy and effects of ketoconazole capsules?
The efficacy of ketoconazole capsules is to treat infections of the skin, hair, and nails (dermatophytosis, onychomycosis, paronychia, tinea versicolor, chronic mucocutaneous candidiasis, etc.) caused by dermatophytes and (or) yeasts. When local treatment is ineffective or it is difficult to apply the drug due to factors such as the location, area, and depth of the infection, this drug can be used for treatment. Gastrointestinal yeast infection.
1. Ketoconazole capsules are synthetic imidazole dioxane derivatives with antibacterial and fungicidal activity against dermatophytes, yeasts (Candida, Pityrosporum, Torulopsis, Cryptococcus), dimorphic fungi, and fungi. Ketoconazole capsules are less sensitive to Aspergillus, Trichophyton schenckii, certain dark-colored fungi, and Mucorales, but are an exception for Entomophthorales. Ketoconazole capsules inhibit the biosynthesis of ergosterol in fungi and change the composition of other lipid compounds in the cell membrane. 2. Long-term toxicity tests in animals show that ketoconazole capsules can significantly increase alkaline phosphatase levels and alter liver cell morphology. Ketoconazole capsules can inhibit the biosynthesis of triglycerides and phospholipids in fungi, inhibit the activity of oxidases and peroxidases, cause accumulation of hydrogen peroxide in the cell, leading to变性 of cell submicrostructure and cell necrosis. For Candida albicans, it can inhibit the process of its transformation from spore to invasive hyphae.
Long-term use of ketoconazole capsules may cause certain side effects. Adverse reactions such as gastrointestinal discomfort, nausea, headache, dizziness, rash, and itching may occur. A few patients may experience side effects such as hair loss, urticaria, and drug rash. A few patients may have allergic reactions and reports of liver damage. In rare cases, when the therapeutic dose exceeds the recommended 0.2g or 0.1g per day, reversible male breast feminization and seminal fluid deficiency may occur.