Invasive digital and toe papillary adenocarcinoma

　　The etiology of invasive digital and toe papillary adenocarcinoma is not yet clear, and it may be related to environmental factors, genetic factors, dietary factors, and emotional and nutritional factors during pregnancy.

　　Due to the ulceration and erosion of the skin and mucosa, the integrity of the skin is destroyed, so it can be induced by scratching by the patient, leading to bacterial infection or fungal infection of the skin, usually secondary to weakened physique, or long-term use of immunosuppressants, or patients with gray nail fungus and other fungal infections. If bacterial infection occurs, there may be symptoms such as fever, skin swelling, erosion, and purulent secretion. Severe cases can lead to sepsis, so it should attract the attention of clinical doctors. At the same time, because the disease can lead to secondary lung metastasis, it can also form secondary lung cancer.

　　This disease presents as a solitary nodule, which can cause ulcers and bleeding, often invading the nail bed of the fingers (toes) and the joint cavity between the distal fingers (toes). Most cases occur in patients around the age of 50, 50% can recur, and less than 50% occur with metastasis, especially lung metastasis, so all patients should have a chest X-ray taken.

　　There are no effective preventive measures for invasive digital papillary adenocarcinoma, and early detection and early diagnosis are the key to the prevention and treatment of the disease. It mainly focuses on preventing various factors that may lead to invasive digital papillary adenocarcinoma. Pay attention to personal and environmental hygiene in daily life, avoid drug abuse, and pay attention to personal protection when working in harmful environments.

　　The pathological examination of this disease shows that there are small papillae extending into large cystic cavities under the microscope. In addition, there are polygonal cell solid nests and irregularly infiltrative tubules surrounding the dermis and subcutaneous tissue, and pathological nuclear division and focal necrosis can be seen.

　　The diet of patients with invasive digital papillary adenocarcinoma should be light, with more vegetables and fruits, reasonable dietary搭配, and attention should be paid to adequate nutrition. Patients should avoid smoking and drinking, spicy food, and cold food.

　　The etiology of invasive digital papillary adenocarcinoma is not yet clear, so it is impossible to treat the disease according to the etiology. The main treatment method for this disease is surgery, including complete resection or extensive local resection, and amputation may be necessary if required.