Pregnancy complicated with mycoplasma infection

　　1. Direct transmission, i.e., sexual transmission, is the main route of transmission for UU and CT.

　　2. Indirect transmission UU and CT can be transmitted through contact with items contaminated with patient secretions, such as bathwater, shared towels, and other ways. It is less common in adults.

　　3. UU and CT can be transmitted to the fetus and newborn through intrauterine, birth canal, and postpartum infections, with birth canal infection being the main route.

　　1. After infection, UU and MH can invade the amniotic membrane and damage the placenta between 16-20 weeks of pregnancy, causing chorioamnionitis, leading to late miscarriage, preterm birth, or stillbirth.

　　2. Newborns, especially premature infants, can develop mycoplasma pneumonia and chronic pneumonia after UU infection.

　　3. MH can lead to postpartum pelvic inflammation and postpartum mycoplasma bacteremia, as well as neonatal mycoplasma bacteremia.

　　4. Postpartum breastfeeding and other contact or airborne infections caused by MP can lead to neonatal pneumonia.

      1. Cervical mucositis

　　Mycoplasma hominis infection often has no symptoms, while Chlamydia trachomatis infection, 70% to 90% have no clinical symptoms. If symptoms occur, they may include increased vaginal discharge, mucopurulent discharge, and bleeding after sexual intercourse.

　　2. Endometritis

　　It is characterized by lower abdominal pain, increased vaginal discharge, and irregular vaginal bleeding, among other symptoms.

　　3. Salpingitis

　　It is characterized by long-term mild lower abdominal pain, low fever, and persistent symptoms that do not improve, which can also manifest as widespread adhesions in the pelvis.

　　1. Engage in physical exercise actively. Plan to exercise regularly, keep the indoor air fresh and at a comfortable temperature while sleeping, and open the window for indirect ventilation at least. Make full use of sunbathing, air bathing, and water bathing. Strengthening physical fitness is the most important factor in preventing diseases.

　　2. Practice hygiene to avoid cross-infection. Avoid crowded places with poor ventilation such as cinemas, department stores, supermarkets, and avoid places with a high concentration of people. Try to avoid contacting patients, seek medical attention as close to home as possible, and minimize visits to large hospitals to shorten waiting times. In the past, it was believed that respiratory diseases were only transmitted through respiratory secretions, but recent studies have confirmed that contact transmission is an important mode of transmission. It is especially important to remind that passive smoking by children increases the risk of respiratory diseases in children.

　　3. Drug prevention Some traditional Chinese and Western medicines can improve the body's cellular and humoral immune function, and it is best to take medication under a doctor's guidance. Vaccination is currently used in some places with attenuated virus vaccines, but it has not been widely applied; vaccines designed for prevention have a protection rate of only 50%, and there are no systematic reports on antibiotic prevention.

　　1. Mycoplasma culture

　　Culturing of vaginal and urethral secretions in combination can achieve a higher positive rate.

　　2. Serological examination

　　The levels of MH and UU serum-specific antibodies in asymptomatic women's serum are low, and the serum antibodies can significantly increase after re-infection.

　　3. Specific IgM

　　Elevated neonatal specific IgM has a certain predictive effect on mycoplasma infection, but none of them have become routine detection methods.

　　4. PCR detection

　　More sensitive, specific, and rapid than the culture method, it has reference value for clinical diagnosis.

　　Diet should be light and non-greasy, meeting nutritional needs while also enhancing appetite. White rice porridge, millet porridge, soybean porridge, and side dishes such as sweet sauce vegetables, radish, pickled vegetables, or bean curd can be provided, with a preference for lightness and freshness. Pay attention to the diet related to medication. Increase individual disease resistance, pay attention to nutrition, and rationally allocate diet. Actively exercise and plan to exercise regularly daily; keep the indoor air fresh and temperature suitable during sleep, and at least indirect ventilation.

　　MH or UU are sensitive to various antibiotics, and drugs acting on ribosomes are often used. Pregnant women should take erythromycin 250mg, four times a day, orally, for 14 consecutive days; non-pregnant individuals can choose tetracycline or clindamycin.

　　For neonatal mycoplasma infection: erythromycin 25-40mg/(kg·d), administered intravenously or orally in four divided doses, for 7-14 days.