Vulvar eccrine porocarcinoma

　　1, Etiology

　　A considerable number of patients have a family history of genetic factors, indicating that part of the disease is related to genetic factors. There are reports of three people in the same family suffering from eccrine porocarcinoma, or there are other nevus-like tumors (such as trichilemmoma, sebaceous adenoma, etc.) in the family. Diffuse familial eccrine porocarcinoma is an autosomal dominant inheritance. Since the disease is more common in women, and the rash increases during puberty, pregnancy, premenstrual period, or when using female hormones, it suggests that vulvar eccrine porocarcinoma is related to endocrine disorders.

　　2, Pathogenesis

　　The tumor is located in the superficial dermis, and multiple basophilic epithelial cells are aggregated into solid cell strands or cystic expansion and ductal embedding in the fibrous matrix in the middle and upper dermis. The duct wall is usually lined with two rows of epithelial cells, and in most cases, the outer cells are flat, with pale red cytoplasm and small nuclei. The lumen is filled with homogeneous eosinophilic material and fine granular degenerative material, and the inner cells have secretory activity. The cell strands can be solid masses, or one end is a solid strand, and the other end is duct-like, resembling a comma or tadpole, which is quite characteristic.

　　It can be complicated with the following diseases:

　　1, Nodular eccrine porocarcinoma: When people experience mental trauma, overwork, menstrual period, or endocrine disorders, which lead to decreased body immunity, the rash can gradually increase or enlarge, or several merge into a large nodular eccrine porocarcinoma, making the treatment more difficult and the treatment time longer.

　　2, Infection: If not treated properly, it can also cause pathogenic bacteria to invade the wound, causing infection.

　　Vulvar eccrine porocarcinoma generally does not have自觉symptoms, in summer, some skin lesions have mild swelling, feel itchy, the skin lesions often gradually increase in size, but stop growing when reaching a certain size, and rarely regress spontaneously, without a tendency to self-heal, the course of the disease is slow, and can last for decades. The main occurrence sites of vulvar eccrine porocarcinoma are the labia majora, mons pubis, perineum, and a few cases can be seen on the labia minora and clitoris. The skin lesions are skin-colored, pale red, or light brown papules or nodules, ranging from needle tip to small soybean size, with a smooth surface and waxy luster. Small papules, nodules are often larger than those in other parts of the eccrine porocarcinoma, can merge into plaques, the number varies from several to hundreds, can be scattered or clustered, the rash is affected by the menstrual cycle, and can increase before menstruation.

　　Prevention and health care for vulvar eccrine cystic adenoma:

　　1. Be cautious with female hormones. If there are any abnormal skin lesions, seek medical treatment early and do a good follow-up.

　　2. Pay attention to keeping the vulvar area clean and dry. If there is any abnormal discharge, pay attention to it and go to the hospital for corresponding examinations.

　　3. Pay attention to nutrition, enhance physical fitness. Eat more foods rich in vitamins and proteins, pay attention to work and rest, exercise more, and rest more.

　　4. Regular physical examinations, pay attention to wound protection, and prevent the occurrence of infection.

　　In addition to clinical manifestations, the following related examination methods are used for the diagnosis of vulvar eccrine cystic adenoma:

      1. Hormonal level monitoring, tumor marker examination.

　　2. Histopathological examination.

　　One, health care and food therapy for the prevention of vulvar tumors

　　1. Sophora Root Egg: 2 eggs, 60 grams of brown sugar, 60 grams of sophora root. Boil sophora root to get a concentrated juice, add the beaten eggs and brown sugar, and cook until done. Eat the egg and drink the soup. Take once a day, 6 days as a course. It has the effect of clearing heat, detoxifying, drying dampness, and healing sores, and can be used for the prevention and treatment of vulvar ulcers.

　　2. Gentian Root Egg: 10 grams of gentian root, 3 eggs, 30 milliliters of honey. Boil gentian root water and remove the dregs, beat the eggs to form a pouch, add honey, and eat on an empty stomach. Take once a day, 5 days as a course. It has the effect of clearing heat, removing dampness, and healing sores.

　　3. Chinese Cabbage and Mung Bean Sprout Drink: 1 root of Chinese cabbage, 30 grams of mung bean sprouts. Clean the root of the Chinese cabbage and slice, clean the mung bean sprouts and put them into the pot together, add an appropriate amount of water, boil for 15 minutes, remove the dregs and take the juice, drink as tea at any time. It has the effect of clearing heat and removing dampness, and can be used for the treatment of vulvar ulcers.

　　4. Rock Candy Winter Melon Soup: 30 grams of winter melon seeds, 30 grams of rock candy. Clean the winter melon seeds, grind into coarse powder, add rock candy, pour one bowl of boiling water, put into an earthen pot, and simmer over low heat. Take two times a day, for several days. It has the effect of clearing heat, removing dampness, and stopping leukorrhea, and can be used for the treatment of vaginal itching.

　　5. Chrysanthemum Stomach: 1 stomach, 30 grams of chrysanthemum seeds, 10 grams of dioscorea opposita. Clean the stomach, add water, and boil with the last two herbs together. Discard the herbs and eat the stomach. It has the effect of kidney-nourishing and wind-relieving itching. Used for the prevention and treatment of atrophic vulvar leukoplakia.

　　6. Goji Berry Porridge: 20 grams of goji berries, an appropriate amount of rice. Cook into porridge for consumption.

　　Two, what to eat for vulvar eccrine cystic adenoma that is good for the body

　　1. Eat more foods that have anti-tumor effects: horseshoe crab, sea horse, dragon pearl tea, and hawthorn.

　　2. For bleeding, it is advisable to eat goat blood, snails, dried seaweed, cuttlefish, shepherd's purse, lotus root, mushrooms, malan tou, shi er, and jupi.

　　3. For infections, it is recommended to eat eels, clam, water snake, needlefish, carp, kudzu, celery, sesame, buckwheat, rapeseed, toon, red beans, and mung beans.

　　4. For abdominal pain and distension, it is advisable to eat pork kidneys, bayberries, hawthorn, tangerine paste, walnuts, and chestnuts.

　　Three, it is best not to eat certain foods for vulvar eccrine cystic adenoma.

　　1. Avoid smoking and drinking.

　　2. Avoid刺激性食物 such as scallions, garlic, and peppers.

　　3. Avoid greasy, fried, and pickled foods.

　　4. Avoid warm and activating blood foods such as mutton, dog meat, chives, and pepper.

　　Traditional Chinese medicine treatment for vulvar syringoma Syringoma is a benign skin accessory tumor. It is detrimental to aesthetic appearance when occurring on the forehead and face, and it often causes varying degrees of itching when occurring on the vulva.

　　Traditional Chinese medicine believes that the occurrence of syringoma may be due to liver depression and qi stagnation with blood stasis, or due to the aggregation of damp-heat in the liver meridian. The treatment of this disease should focus on external treatment, combined with internal administration of traditional Chinese medicine.

　　First, external washing

　　1. Applicable population: Patients with vulvar syringoma accompanied by itching.

　　2. Medication: 30 grams of Sophora flavescens, 30 grams of Raphanus sativus, 30 grams of Lithospermum erythrorhizon, 30 grams of Rheum palmatum, 20 grams of Alumen, 20 grams of Schizonepeta tenuifolia.

　　3. Dosage: Take one dose of decocted water and wash the affected area with a slightly warm solution daily.

　　Second, Wumiao Shuixian Paste

　　1. Effect:

　　Wumiao Shuixian Paste acts directly on the affected area, causing the protein of the lesion tissue to coagulate, blood vessels to occlude, tissue to atrophy, volume to shrink, and keratin to dissolve.

　　It has the effect of eliminating proliferative lesion tissue. Stimulates nerve endings, improves blood circulation, promotes tissue regeneration, accelerates wound healing. Strong antibacterial, anti-inflammatory, rapid healing. Hemostatic, antipruritic, analgesic. No trace after healing. Has the effect of removing decay and generating new tissue, clearing heat and detoxifying.

　　2. Applicable population: Patients with folliculitis, nodular pruritus, common warts, neurodermatitis, and other diseases.

　　3. Method of use:

　　After local skin disinfection, apply Wumiao Shuixian Paste directly to the rash, repeat several times, until a swelling and pale ring appears around the rash. Then, use a dental sanding wheel to remove the rash.

　　Three, Crystal Paste

　　1. Introduction: The main ingredient is 5 liang of lime (hydrated and powdered). It is mainly used for mole removal beauty.

　　2. Method of use: Same as Wumiao Shuixian Paste. In general, Western medical treatment for vulvar syringoma does not require treatment, but electrolysis, electrocautery, and carbon dioxide laser can be used when necessary, but scars are prone to occur.

　　Liquid nitrogen freezing therapy is prone to cause hypopigmentation.

　　When performing liquid nitrogen freezing or laser therapy, attention should be paid to batch treatment and the depth of treatment should be controlled to prevent the formation of obvious scars. Compared with laser therapy, the effect of laser therapy is better and scars are generally not left.

　　If it is inevitable to undergo surgery for resection, it is necessary to make an accurate diagnosis and exclude the possibility of metastatic adenocarcinoma.